BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide

BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide

Like thapsigargin, which is undergoing clinical trials, trilobolide is a natural product with promising anticancer and anti-inflammatory properties. Similar to thapsigargin, it has limited aqueous solubility that strongly reduces its potential medicinal applications. The targeted delivery of hydrophobic drugs can be achieved using liposome-based carriers. Therefore, we designed a traceable lipo...

The Antiinflammatory Sesquiterpene Lactone

Aromaticine, a sesquiterpene lactone from Amblyopappus pusillus

AROMATICINE (SYSTEMATIC NAME: 4a,8-dimethyl-3-methyl-ene-3,3a,4,4a,7a,8,9,9a-octa-hydro-azuleno[6,5-b]furan-2,5-dione), C(15)H(18)O(3), is a natural lactone isolated from Amblyopappus pusillus. The mol-ecular structure and conformation agree with the results of Romo, Joseph-Nathan & Díaz [(1964 ▶). Tetra-hedron, 20, 79-85]. The fused-ring system contains a seven-membered ring in a twist-boat co...

Cynaratriol, a sesquiterpene lactone from Centaurea musimomum

THE TITLE COMPOUND [SYSTEMATIC NAME: 3,8-dihydr-oxy-3-(hydroxy-meth-yl)-9-methyl-6-methyl-enedeca-hydro-azuleno[4,5-b]furan-2(3H)-one], C(15)H(22)O(5), is a sesquiterpene lactone showing the typical tricyclic guaianolide skeleton which has been isolated, together with other related metabolites, from the plant Centaurea musimomum. The present study confirms the mol-ecular structure, assigned by ...

Phytochemical Review Profile of Sesquiterpene Lactone Parthenin

Parthenin (a sesquiterpene lactone) is a major constituent of parthenium hysterophorus –a noxious weed known for its environmental and health hazardous properties. . It is responsible for imparting the several properties to this weed such as allelpathy, autotoxicity and allergencity. Further, anticancerous, antiameobic and antimalarial properties of the weed are also credited to parthenin. The ...